saving data in combo box at runtime

hii, i am having some problem in saving the data in combo box at runtime. i am taking the input from a text box to add item in my combo box, it is saving the data for the same time but when i restart my program these added items are removed automatically.. what to do to add the data permanently?????? if we can do it by making another database then what can be the code? can we make an MS ACCESS file into which we can add item through text box and then fetch that item list using dataenvironment, etc.. please reply........